Common Data Elements (CDEs) Repository

Common Data Elements (CDEs) Repository

The NIH HEAL Initiative’s  aims to harmonize the data collected by the initiative’s studies, enhancing the comparability of various data sets generated by HEAL research.

HEAL researchers and potential applicants conducting research with human participants should also prioritize using the HEAL CDEs. Researchers outside the HEAL Initiative conducting pain research may also be interested in using validated and structured questionnaires.

The 'core' questionnaires in ten domains, demographic information, and opioid usage are required for the human subjects in pain HEAL grants and are organized depending on the type of pain and population being studied.

Description Core or Supplemental Research Topic CDE Files

The Patient Health Questionnaire 2 (PHQ-2) measures the frequency of depressed mood and anhedonia over the past two weeks.

 Adult Acute, Adult Chronic, All Core, Pediatrics Depression

The Pain Catastrophizing Scale Parent (PCS-P) measures the thoughts and feelings that parents may experience when their child is in pain.

 All Core, Pediatrics Pain Catastrophizing

The Pain Catastrophizing Scale 6 (PCS-6) measures the state of mind of a participant in pain that encompasses the different perspectives on worrying.

 Adult Acute, Adult Chronic, All Core Pain Catastrophizing

The Pain Catastrophizing Scale Child (PCS-C) measures the state of mind of a pediatric participant in pain that encompasses the different perspectives on worrying.

 All Core, Pediatrics Pain Catastrophizing

The Opioid MME is the amount of milligrams of morphine an opioid dose is equal to when prescribed. Calculating MME accounts for differences in opioid drug type and strength.

 Adult Acute, Adult Chronic, All Core Opioids

The Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Tool measures the participants tobacco use, alcohol use, prescription medication misuse, and illicit substance use in the past year.

 Adult Acute, Adult Chronic, All Core Substance Use

The Patient Health Questionnaire 9 (PHQ-9) measures the frequency of depressed mood and anhedonia over the past two weeks.

 Adult Acute, Adult Chronic, All Core, Pediatrics, Supplemental Depression

The PROMIS Physical Function 6b assesses physical function through a grading scale of daily living activities.

 Adult Acute, Adult Chronic, All Core Physical Functioning

The NIDA-Modified ASSIST is a self-report measurement to assess participants for risky substance use.

 All Core, Pediatrics Substance Use

The Pain, Enjoyment of Life and General Activity (PEG) scale is used for quickly assessing and monitoring chronic pain.

 Adult Chronic, All Core Pain Intensity

The Generalized Anxiety Disorder 2 (GAD-2) is an initial screening tool for generalized anxiety disorder.

 Adult Acute, Adult Chronic, All Core, Pediatrics Anxiety

The Sleep Duration question measures the average amount of sleep the participant slept each night, in the past month.

 Adult Acute, Adult Chronic, All Core Sleep

The Pain Catastrophizing Scale 13 (PCS-13) measures the state of mind of a participant in pain that encompasses the different perspectives on worrying.

 Adult Acute, Adult Chronic, All Core, Supplemental Pain Catastrophizing

The Brief Pain Inventory (BPI) pain severity subscale assess the severity of the participants pain in the past 7 days.

 All Core, Pediatrics Pain Intensity

The Pediatric Demographics are a set of demographic questions to gain background information on pediatric participants.

 All Core, Pediatrics Demographics

The Brief Pain Inventory (BPI) pain severity questions assess the severity of the participants pain in the past 24 hours.

 Adult Acute, Adult Chronic, All Core, Pediatrics Pain Intensity

The PROMIS Sleep Disturbance 6a scale is composed of 6 items developed to assess the domain of sleep disturbances in the past 7 days.

 Adult Acute, Adult Chronic, All Core Sleep

The Patient Global Impression of Change (PGIC) measures the change of a participant's condition over a certain amount of time.

 Adult Acute, Adult Chronic, All Core, Pediatrics Global Satisfaction with Treatment

The Brief Pain Inventory (BPI) pain interference subscale assess the impact of pain on daily functions.

 Adult Acute, All Core Pain Interference

The Patient Global Impression of Severity (PGIS) measures the severity of a specific condition (a single-state scale).

 All Core, Pediatrics Global Satisfaction with Treatment

The PedsQL Inventory measures the health-related quality of life (HRQOL) in healthy children and adolescents and those with acute and chronic health conditions.

 All Core, Pediatrics Physical Functioning

The Adolescent Sleep Wake Scale 10 (ASWS-10) and Sleep pattern/duration items from the Children's Report of Sleep Patterns (CRSP) measures pediatric participants sleep behaviors and patterns.

 All Core, Pediatrics Sleep

The Adult Demographics measure background information on adult participants.

 Adult Acute, Adult Chronic, All Core Demographics

The World Health Organization Quality of Life (QOL) 2 item assesses quality of life and satisfaction of health.

 Adult Acute, Adult Chronic, All Core Quality of Life

The Generalized Anxiety Disorder 2 (GAD-2) is an initial screening tool for generalized anxiety disorder.

 Adult Acute, Adult Chronic, All Core, Pediatrics Anxiety

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