Common Data Elements (CDEs) Repository

Common Data Elements (CDEs) Repository

The NIH HEAL Initiative’s  aims to harmonize the data collected by the initiative’s studies, enhancing the comparability of various data sets generated by HEAL research.

HEAL researchers and potential applicants conducting research with human participants should also prioritize using the HEAL CDEs. Researchers outside the HEAL Initiative conducting pain research may also be interested in using validated and structured questionnaires.

The 'core' questionnaires in ten domains, demographic information, and opioid usage are required for the human subjects in pain HEAL grants and are organized depending on the type of pain and population being studied.

Description Core or Supplemental Research Topic CDE Files

The Patient Global Impression of Change (PGIC) measures the change of a participant's condition over a certain amount of time.

All Core, Adult Chronic, Adult Acute, Pediatrics Global Satisfaction with Treatment

The Patient Global Impression of Severity (PGIS) measures the severity of a specific condition (a single-state scale).

All Core, Pediatrics Global Satisfaction with Treatment

The Patient Health Questionnaire 2 (PHQ-2) measures the frequency of depressed mood and anhedonia over the past two weeks.

All Core, Adult Chronic, Adult Acute, Pediatrics Depression

The Patient Health Questionnaire 8 (PHQ-8) measures the frequency of depressed mood and anhedonia over the past two weeks.

All Core, Adult Chronic, Adult Acute, Pediatrics, Supplemental Depression

The Adult Demographics are a set of demographic questions to gain background information on adult participants.

All Core, Adult Chronic, Adult Acute Demographics

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